Brevinin-1Sb

Entry Brevinin-1Sb
Peptide names Brevinin-1Sb Brevinin-1BLa
Suborder Neobatrachia
Family Ranidae
Genus Lithobates
Species Lithobates sphenocephalus
Ecozone Nearctic
Distribution Southern New York south along the Atlantic coastal plain to southern Florida, west to eastern Texas, and north to eastern Kansas, southern Illinois, and southern Ohio (excluding most of the Appalachian Mountains); introduced on Grand Bahama Island, Bahamas.
Antimicrobial & other activities antibacterial, antifungal, anticancer
Tissue Skin
Sequence
Length 24
References:
1. for MIC/HC50 J.M. Conlon et al. / Journal of Peptide Research 54 (1999) 522-527. Peptides with antimicrobial activity of the brevinin-1 family isolated from skin secretions of the southern leopard frog, Rana sphenocephala
2. for other activities J.M. Conlon et al. / Toxicon 53 (2009) 699-705. Peptides with potent cytolytic activity from the skin secretions of the North American leopard frogs, Lithobates blairi and Lithobates yavapaiensis


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
BioactiveBrevinin-1Sb24NoFLPAIVGAAAKFLPKIFCAISKKC 17