Temporin-1DRa

Entry Temporin-1DRa
Peptide names Temporin-1DRa
Suborder Neobatrachia
Family Ranidae
Genus Rana
Species Rana draytonii
Ecozone Nearctic
Distribution Mendocino County (California, USA) south along the Pacific coast of the USA to the vicinity of Arroyo Santo Domingo in northern Baja California (Mexico), 0-2440 m elevation. Northern San Joaquin Valley and Sierra Nevada of California. Now extinct in most of southern California as well as from the southern Sierra Nevada.
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin
Sequence
Length 14
References:
1. for MIC/HC50 E. Urban et al. / International Journal of Antimicrobial agents 29 (2007) 317-321. Activities of four frog skin-derived antimicrobial peptides (temporin-1DRa, temporin-1Va and the melittin-related peptides AR-23 and RV-23) against anaerobic bacteria;  J.M. Conlon et al. / Methods 42 (2007) 349-357. Strategies for transformation of naturally-occurring amphibian antimicrobial peptides into therapeutically valuable anti-infective agents


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
BioactiveTemporin-1DRa14YesHFLGTLVNLAKKIL7012.56