Fallaxin

Entry Fallaxin
Peptide names Fallaxin
Suborder Neobatrachia
Family Leptodactylidae
Genus Leptodactylus
Species Leptodactylus fallax
Ecozone Neotropic
Distribution St. Kitts, Montserrat, Guadeloupe, Dominica, and St. Lucia (now extant only on Montserrat and Dominica, Lesser Antilles). Introduced unsuccessfully on Jamaica and Puerto Rico
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence
Length 25
References:
1. for MIC/HC50 L.A. Rollins-Smith et al. / Regulatory Peptides 124 (2005) 173-178. An antimicrobial peptide from the skin secretions of the mountain chicken frog Leptodactylus fallax (Anura:Leptodactylidae)
2. for other activities S.L. Nielsen et al. / Protein Science 16 (2007) 1969-1976. Structure-activity study of the antibacterial peptide fallaxin;  L.A. Rollins-Smith et al. / Regulatory Peptides 124 (2005) 173-178. An antimicrobial peptide from the skin secretions of the mountain chicken frog Leptodactylus fallax (Anura:Leptodactylidae)


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
BioactiveFallaxin25YesGVVDILKGAAKDIAGHLASKVMNKL>200.0040