Tiannanensin

Entry Tiannanensin
Peptide names Tiannanensin Hainanensin-2
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana tiannanensis
Ecozone Indomalaya
Distribution Guangxi and southern Yunnan (Mangla, Pingbian, and Hekou counties) and Hainan Island, China; Phou Dendin National Biodviersty Conservation area, Phongsaly Province, Laos; northern, north-central, and northeastern Vietnam in and around montane rivers as well as in the adjacent forest, 120?1000 m elevation
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin
Sequence MFTMKKSMLLLLFLGTINLSLSEQERDAEEERRDDPEERDAEVEKRAILTTLANWARKFL
Length 60
Signal peptide class Class-1
References:
1. for MIC/HC50 W. He et al. / Biochimie (2011) in press. Host defense peptides in skin secretions of Odorrana tiannanensis: Proof for other survival strategy of the frog than merely anti-microbial


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTMKKSMLLLLFLGTINLSLS    
Prepro24 EQERDAEEERRDDPEERDAEVEKR   
BioactiveTiannanensin14YesAILTTLANWARKFL  46