Insulin-releasing-peptide

Entry Insulin-releasing-peptide
Peptide names Insulin-releasing-peptide Dermaseptin-B4 Dermaseptin B4 Dermaseptin-2 IRS Dermaseptin-TR1
Suborder Neobatrachia
Family Hylidae
Genus Phyllomedusa
Species Phyllomedusa trinitatis
Ecozone Neotropic
Distribution Trinidad and the coastal mountains in northern Venezuela
Antimicrobial & other activities antibacterial, insulin releasing
Tissue Skin
Sequence
Length 28
References:
1. for MIC/HC50 S. Charpentier et al. / The Journal of Biological Chemistry 273 (1998) 14690-14697. Structure, synthesis, and molecular cloning of dermaseptins B, a family of skin peptide antibiotics
2. for other activities M. Amiche et al. / Peptides 29 (2008) 2074-2082. A consistent nomenclature of antimicrobial peptides isolated from frogs of the subfamily Phyllomedusinae


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
BioactiveInsulin-releasing-peptide28YesALWKDILKNVGKAAGKAVLNTVTDMVNQ 53