Preprobradykinin-1

Entry Preprobradykinin-1
Uniprot code A0AEI1
Fasta A0AEI1
Peptide names V1,T6 bradykinin Preprobradykinin-1 V1-bradykinin
Suborder Neobatrachia
Family Ranidae
Genus Hylarana
Species Hylarana guentheri
Ecozone Indomalaya
Distribution Central Vietnam throughout southern China (north to Yangtze River), including Hainan and Taiwan; introduced onto Guam
Antimicrobial & other activities contraction of small intestine smooth muscle cells, relaxation of arterial smooth muscle cells
Tissue Skin, Venom
Sequence MLTLKKSLLLLFFFGTISLSLCEQERDADEDENESRTVRVPPGFTPFRIAPASSLKRNAD
ADETERRISKRPPGFSPFRIAPASSLKRNADADETERRISKRPPGFSPFRIAPASSLKRN
ADADETERRISKRPPGFSPFRIAPASSLKRNADEDENESRMVRVPPGFSPFRIAPEIV
Length 178
Signal peptide class Class-1
References:
2. for other activities T. Chen et al. / Peptides 23 (2002) 1547-1555. Bradykinins and their precursor cDNAs from the skin of the fire-bellied toad (Bombina orientalis)


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MLTLKKSLLLLFFFGTISLSLC    
Prepro17 EQERDADEDENESRTVR   
BioactiveV1,T6 bradykinin9NoVPPGFTPFR   
Prepro22 IAPASSLKRNADADETERRISK   
Bioactivebradykinin9NoRPPGFSPFR   
Prepro22 IAPASSLKRNADADETERRISK   
Bioactivebradykinin9NoRPPGFSPFR   
Prepro22 IAPASSLKRNADADETERRISK   
Bioactivebradykinin9NoRPPGFSPFR   
Prepro22 IAPASSLKRNADEDENESRMVR   
BioactiveV1-bradykinin9NoVPPGFSPFR