Entry | Preprobradykinin-1 |
Uniprot code | A0AEI1 |
Fasta | A0AEI1 |
Peptide names | V1,T6 bradykinin Preprobradykinin-1 V1-bradykinin |
Suborder | Neobatrachia |
Family | Ranidae |
Genus | Hylarana |
Species | Hylarana guentheri |
Ecozone | Indomalaya |
Distribution | Central Vietnam throughout southern China (north to Yangtze River), including Hainan and Taiwan; introduced onto Guam |
Antimicrobial & other activities | contraction of small intestine smooth muscle cells, relaxation of arterial smooth muscle cells |
Tissue | Skin, Venom |
Sequence | MLTLKKSLLLLFFFGTISLSLCEQERDADEDENESRTVRVPPGFTPFRIAPASSLKRNAD ADETERRISKRPPGFSPFRIAPASSLKRNADADETERRISKRPPGFSPFRIAPASSLKRN ADADETERRISKRPPGFSPFRIAPASSLKRNADEDENESRMVRVPPGFSPFRIAPEIV |
Length | 178 |
Signal peptide class | Class-1 |
References: | |
2. for other activities | T. Chen et al. / Peptides 23 (2002) 1547-1555. Bradykinins and their precursor cDNAs from the skin of the fire-bellied toad (Bombina orientalis) |
Segment type | Name | Length | Amidated | Sequence | HC50 (μM) | MIC E. coli (μM) | MIC S. aureus (μM) |
Signal | 22 | MLTLKKSLLLLFFFGTISLSLC | |||||
Prepro | 17 | EQERDADEDENESRTVR | |||||
Bioactive | V1,T6 bradykinin | 9 | No | VPPGFTPFR | |||
Prepro | 22 | IAPASSLKRNADADETERRISK | |||||
Bioactive | bradykinin | 9 | No | RPPGFSPFR | |||
Prepro | 22 | IAPASSLKRNADADETERRISK | |||||
Bioactive | bradykinin | 9 | No | RPPGFSPFR | |||
Prepro | 22 | IAPASSLKRNADADETERRISK | |||||
Bioactive | bradykinin | 9 | No | RPPGFSPFR | |||
Prepro | 22 | IAPASSLKRNADEDENESRMVR | |||||
Bioactive | V1-bradykinin | 9 | No | VPPGFSPFR |