Entry
Amolopin-2a
Uniprot code
A0SN45
Fasta
A0SN45
Peptide names
Amolopin-2a Temporin-ALa Temporin-MT3
Suborder
Neobatrachia
Family
Ranidae
Genus
Amolops
Species
Amolops loloensis
Ecozone
Palearctic
Distribution
High-gradients streams in Zhaojue, Mianning, Hongya, Luding, and Baoxing in southern Sichuan, China, 1840-3700 m elevation
Antimicrobial & other activities
antibacterial, antifungal, mast cell degranulation, histamine releasing
Tissue
Skin
Sequence
MFTLKKSLLLLFFLGTINLSLCEQERNAEEERRDEPDERNAEVEKRFLPIVGKLLSGLSG
Length
64
Signal peptide class
Class-1
References:
1. for MIC/HC50
Yi Lu et al. / Peptides 27 (2006) 3085-3091. Two families of antimicrobial peptides with multiple functions from skin of rufous-spotted torrent frog, Amolops loloensis
Segment type
Name
Length
Amidated
Sequence
HC50 (μM)
MIC E. coli (μM)
MIC S. aureus (μM)
Signal
22
MFTLKKSLLLLFFLGTINLSLC
Prepro 24 EQERNAEEERRDEPDERNAEVEKR Bioactive Amolopin-2a 16 Yes FLPIVGKLLSGLSGLL 1.84 1.23