Preprotemporin-1SKa

Entry Preprotemporin-1SKa
Uniprot code A1IKN3
Fasta A1IKN3
Peptide names Preprotemporin-1SKa Temporin-1SKa
Suborder Neobatrachia
Family Ranidae
Genus Rana
Species Rana sakuraii
Ecozone Palearctic
Distribution Montane regions of central Honshu from Kanto through Chubu to Kinki Districts, Japan
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin
Sequence MFTLKKSLLLLFFLGTINLSLCEEERNAEEERRDDPEERDVEVEKRFLPVILPVIGKLLN
GILGK
Length 65
Signal peptide class Class-1
References:
1. for MIC/HC50 H. Suzuki et al. / Peptides 28 (2007) 505-514. Expression of genes encoding antimicrobial and bradykinin-related peptides in skin of the stream brown frog Rana sakuraii


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSLLLLFFLGTINLSLC    
Prepro24 EEERNAEEERRDDPEERDVEVEKR   
BioactivePreprotemporin-1SKa17YesFLPVILPVIGKLLNGIL >50.0025