Nigrocin-2

Entry Nigrocin-2
Uniprot code A1JUI6
Fasta A1JUI6
Peptide names Nigrocin-2 Nigrocin-2H Nigrocin-2P
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana livida
Ecozone Indomalaya
Distribution Known definitely only from the type locality (Myanmar) near the Thai border, although animals have been referred, apparently in error, to this taxon, from northeastern India to southern China
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MFTLKKSLLLLFFLGMVSLALCEQERDANEEERRDELDERDVEAIKRGLLSKVLGVGKKV
LCGVSGLC
Length 68
Signal peptide class Class-1
References:
1. for MIC/HC50 L. Wang et al. / FEBS Journal 277 (2010) 1519-1531. Nigrocin-2 peptides from Chinese Odorrana frogs - integration of UPLC/MS/MS with molecular cloning in amphibian skin peptidome analysis


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSLLLLFFLGMVSLALC    
Prepro25 EQERDANEEERRDELDERDVEAIKR   
BioactiveNigrocin-221NoGLLSKVLGVGKKVLCGVSGLC 515