Entry
Esculentin-2-OG10
Uniprot code
A6MAW7
Fasta
A6MAW7
Peptide names
Esculentin-2-OG10 Esculentin-2-OG7 Brevinin-2GRc Esculentin-2-OA3
Suborder
Neobatrachia
Family
Ranidae
Genus
Odorrana
Species
Odorrana grahami
Ecozone
Palearctic, Indomalaya
Distribution
Sichuan, Guizhou, and central and western Yunnan, China; a distantly alloparic population present in southern Shanxi, China: presumably to be found in eastern Myanmar along the Yunna, China, border; reported in Lao Cai and Lai Chau provinces, Vietnam, 1150-3200 m elevation
Antimicrobial & other activities
antibacterial
Tissue
Skin
Sequence
MFTMKKSLLVLFFLGTTSLSLCQEERAADEEDNGEVGEVKRGLFTLIKGAAKLIGKTVAK
Length
78
Signal peptide class
Class-1
References:
1. for MIC/HC50
J.M. Conlon et al. / Peptides 27 (2006) 2111-2117. Antimicrobial peptides from diverse families isolated from the skin of the Asian frog, Rana grahami
Segment type
Name
Length
Amidated
Sequence
HC50 (μM)
MIC E. coli (μM)
MIC S. aureus (μM)
Signal
22
MFTMKKSLLVLFFLGTTSLSLC
Prepro 19 QEERAADEEDNGEVGEVKR Bioactive Esculentin-2-OG10 37 No GLFTLIKGAAKLIGKTVAKEAGKTGLELMACKITNQC 100 12.5 50