Nigrosin-OG20

Entry Nigrosin-OG20
Uniprot code A6MAY8
Fasta A6MAY8
Peptide names Grahamin-1 Grahamin-2 Nigrocin-2GRa Nigrosin-OG20 Nigrosin-RA2
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana grahami
Ecozone Palearctic, Indomalaya
Distribution Sichuan, Guizhou, and central and western Yunnan, China; a distantly alloparic population present in southern Shanxi, China: presumably to be found in eastern Myanmar along the Yunna, China, border; reported in Lao Cai and Lai Chau provinces, Vietnam, 1150-3200 m elevation
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin
Sequence MFTMKKSLLLLFFLGTINLSLCQDETNAEEERRDEEVAKMEEVKRGLLSGILGAGKHIVC
GLSGLC
Length 66
Signal peptide class Class-1
References:
1. for MIC/HC50 X. Xu et al. / Toxicon 47 (2006) 459-464. Two antimicrobial peptides from skin secretions of Rana grahami


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTMKKSLLLLFFLGTINLSLC    
Prepro23 QDETNAEEERRDEEVAKMEEVKR   
BioactiveNigrosin-OG2021NoGLLSGILGAGKHIVCGLSGLC 2.551.27