Brevinin-1PLc

Entry Brevinin-1PLc
Uniprot code A7WNV4
Fasta A7WNV4
Peptide names Brevinin-1PLc
Suborder Neobatrachia
Family Ranidae
Genus Lithobates
Species Lithobates palustris
Ecozone Palearctic
Distribution Eastern North America, from southern Quebec through southern Ontario (Canada) south through extreme eastern Minnesota and on to East Texas then east to South Carolina (USA), extreme western Florida, and north to Nova Scotia (Canada)
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin
Sequence MFTLKKSMLLLFFLGTINLSLCEEERNAEEERRDEPDEMDVEVEKRFLPVIAGVAAKFLP
KIFCAITKKC
Length 70
Signal peptide class Class-1
References:
1. for MIC/HC50 Y.J. Basir et al. / Biochimica et Biophysica Acta 1543 (2000) 95-105. Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSMLLLFFLGTINLSLC    
Prepro24 EEERNAEEERRDEPDEMDVEVEKR   
BioactiveBrevinin-1PLc24NoFLPVIAGVAAKFLPKIFCAITKKC 74