Temporin-1PLa

Entry Temporin-1PLa
Uniprot code A7WNV7
Fasta A7WNV7
Peptide names Temporin-1AM Temporin-1PLa Temporin-1V
Suborder Neobatrachia
Family Ranidae
Genus Lithobates
Species Lithobates palustris
Ecozone Palearctic
Distribution Eastern North America, from southern Quebec through southern Ontario (Canada) south through extreme eastern Minnesota and on to East Texas then east to South Carolina (USA), extreme western Florida, and north to Nova Scotia (Canada)
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MFTSKKSLLLLFFLGTINLSLCEEERDADEEERRDDPDEMNVEVEKRFLPLVGKILSGLI
GK
Length 62
Signal peptide class Class-1
References:
1. for MIC/HC50 Y.J. Basir et al. / Biochimica et Biophysica Acta 1543 (2000) 95-105. Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTSKKSLLLLFFLGTINLSLC    
Prepro25 EEERDADEEERRDDPDEMNVEVEKR   
BioactiveTemporin-1PLa13YesFLPLVGKILSGLI  70