Temporin-1AM

Entry Temporin-1AM
Uniprot code B0B2H5
Fasta B0B2H5
Peptide names Temporin-1AM Temporin-1PLa Temporin-1V
Suborder Neobatrachia
Family Ranidae
Genus Rana
Species Rana amurensis
Ecozone Palearctic
Distribution Western Siberia east to Sakhalin Island, northern and eastern Mongolia, northeastern China and North Korea, north to beyond the Arctic Circle (northernmost 71 degrees N)
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MFTLKKSLLLLFFLGTINLSLCEEERDADEEERRDDPDEMNVEVEKRFLPLVGKILSGLI
GK
Length 62
Signal peptide class Class-1
References:
1. for MIC/HC50 Y.J. Basir et al. / Biochimica et Biophysica Acta 1543 (2000) 95-105. Multiple antimicrobial peptides and peptides related to bradykinin and neuromedin N isolated from skin secretions of the pickerel frog, Rana palustris


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSLLLLFFLGTINLSLC    
Prepro25 EEERDADEEERRDDPDEMNVEVEKR   
BioactiveTemporin-1AM13YesFLPLVGKILSGLI  70