Nigrocin-2S

Entry Nigrocin-2S
Uniprot code B0B2H7
Fasta B0B2H7
Peptide names Nigrocin-2S
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana schmackeri
Ecozone Palearctic, Indomalaya
Distribution Southern and south-central China in Henan, Shaanxi, Gansu, Sichuan, Guizhou, Hubei, Anhui, Jiangsu, Zhejiang, Hunan, Guangdong and Guangxi Provinces, at 200-1400 m elevation; reports from Vietnam and Thailand require confirmation
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MFTLKKSILLLFFLGTINLSLCQDETNAEEERRDEEVAKMEEIKRGILSGILGAGKSLVC
GLSGLC
Length 66
Signal peptide class Class-1
References:
1. for MIC/HC50 L. Wang et al. / FEBS Journal 277 (2010) 1519-1531. Nigrocin-2 peptides from Chinese Odorrana frogs - integration of UPLC/MS/MS with molecular cloning in amphibian skin peptidome analysis


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSILLLFFLGTINLSLC    
Prepro23 QDETNAEEERRDEEVAKMEEIKR   
BioactiveNigrocin-2S21NoGILSGILGAGKSLVCGLSGLC 50>100.00