Entry | Kininogen-1 |
Uniprot code | B2FUW2 |
Fasta | B2FUW2 |
Peptide names | RR-13 Kininogen-1 bradykinin AA-15 |
Suborder | Neobatrachia |
Family | Ranidae |
Genus | Rana |
Species | Rana chensinensis |
Ecozone | Palearctic |
Distribution | Eastern Mongolia; north-central China (Shanxi) south to Sichuan and Hubei |
Antimicrobial & other activities | contraction of small intestine smooth muscle cells, relaxation of arterial smooth muscle cells |
Tissue | Skin |
Sequence | MFTLKKSLLLLFFLGTISLSLCEQERDADEDEYAGDAKAEDVKRAGYSRVISLPAGLSPL RIAPASSRMIRRPPGFSPFRIAPASTLKRDADEDEYAGEAKAEDVKRAGIRRPPGFSPLR IAPASSRMIRRPPGFSPFRIAPAIV |
Length | 145 |
Signal peptide class | Class-1 |
References: | |
2. for other activities | T. Chen et al. / Peptides 23 (2002) 1547-1555. Bradykinins and their precursor cDNAs from the skin of the fire-bellied toad (Bombina orientalis) |
Segment type | Name | Length | Amidated | Sequence | HC50 (μM) | MIC E. coli (μM) | MIC S. aureus (μM) |
Signal | 22 | MFTLKKSLLLLFFLGTISLSLC | |||||
Prepro | 26 | EQERDADEDEYAGDAKAEDVKRAGYS | |||||
Bioactive | RR-13 | 13 | No | RVISLPAGLSPLR | |||
Prepro | 10 | IAPASSRMIR | |||||
Bioactive | bradykinin | 9 | No | RPPGFSPFR | |||
Prepro | 27 | IAPASTLKRDADEDEYAGEAKAEDVKR | |||||
Bioactive | AA-15 | 15 | No | AGIRRPPGFSPLRIA | |||
Prepro | 8 | PASSRMIR | |||||
Bioactive | bradykinin | 9 | No | RPPGFSPFR |