| Entry | Kininogen-1 |
| Uniprot code | B2G280 |
| Fasta | B2G280 |
| Peptide names | c-terminally extended bradykinin T6-bradykinin Kininogen-1 V1 T6-bradykinin |
| Suborder | Neobatrachia |
| Family | Ranidae |
| Genus | Lithobates |
| Species | Lithobates pipiens |
| Ecozone | Nearctic |
| Distribution | Southern Canada (southeastern British Columbia to southern Northern Territory east to Labrador and Nova Scotia) south through eastern Washington eastern Oregon, Nevada and adjacent California to northern Arizona, northern New Mexico (with islolated populations along the Rio Grande south to Las Cruces), thence east-northeast to central Nebraska, Ohio, northern Kentucky, West Virginia, and New England, USA |
| Antimicrobial & other activities | contraction of small intestine smooth muscle cells, relaxation of arterial smooth muscle cells |
| Tissue | Skin |
| Sequence | MFTLKKSLLLLFFLGTINLSLCEQERDADEDENEREAKVEDVKRAGYSRMIRRPPGFSPF RIAPASSLKRDADEDEDAGEAKTEDVKRAGYSRMIRRPPGFTPFRIAPASTLKRDRDEDE YAGQAKAEDVKRAGYSRMIRVPPGFTPFRIAPASTLKRDADEDEYAGEAKAEDVKRAGYS RMIRRPPGFSPFRIAPASTLKRDADEDEYAGEAKVEDVKRAGYSRMIRRPPGFSPFRIAP ASTLKRDSDEDEYAGEAKAEDVKRAGYSRMIRRPPGFSPFRIAPAIV |
| Length | 287 |
| Signal peptide class | Class-1 |
| References: | |
| 2. for other activities | T. Chen et al. / Peptides 23 (2002) 1547-1555. Bradykinins and their precursor cDNAs from the skin of the fire-bellied toad (Bombina orientalis) |
| Segment type | Name | Length | Amidated | Sequence | HC50 (μM) | MIC E. coli (μM) | MIC S. aureus (μM) |
| Signal | 22 | MFTLKKSLLLLFFLGTINLSLC | |||||
| Prepro | 30 | EQERDADEDENEREAKVEDVKRAGYSRMIR | |||||
| Bioactive | c-terminally extended bradykinin | 14 | No | RPPGFSPFRIAPAS | |||
| Prepro | 30 | SLKRDADEDEDAGEAKTEDVKRAGYSRMIR | |||||
| Bioactive | c-terminally extended T6-bradykinin | 14 | No | RPPGFTPFRIAPAS | |||
| Prepro | 30 | TLKRDRDEDEYAGQAKAEDVKRAGYSRMIR | |||||
| Bioactive | V1 T6-bradykinin | 9 | No | VPPGFTPFR | |||
| Prepro | 35 | IAPASTLKRDADEDEYAGEAKAEDVKRAGYSRMIR | |||||
| Bioactive | c-terminally extended bradykinin | 14 | No | RPPGFSPFRIAPAS | |||
| Prepro | 30 | TLKRDADEDEYAGEAKVEDVKRAGYSRMIR | |||||
| Bioactive | c-terminally extended bradykinin | 14 | No | RPPGFSPFRIAPAS | |||
| Prepro | 30 | TLKRDSDEDEYAGEAKAEDVKRAGYSRMIR | |||||
| Bioactive | bradykinin | 9 | No | RPPGFSPFR |