Maximin 12/H3

Entry Maximin 12/H3
Uniprot code B5L112
Fasta B5L112
Peptide names Maximin 12 Maximin 12/H3 Maximin H3
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial; Maximin H3: antibacterial, antifungal
Tissue Skin
Sequence MNFKYIVAVSFLIASAYARSVQNDEQSLSQRDVLEEEESLREIRGIGGKILSGFKTALKG
AAKELAFTYLHRKRTAEDHEVMKRLEAVMRDLDSLDHPEEAFERETRGFNQEEIANLFTK
KEKRILGPVLGLVGNALGGLIKKIG
Length 145
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro26 RSVQNDEQSLSQRDVLEEEESLREIR   
BioactiveMaximin 1227YesGIGGKILSGFKTALKGAAKELAFTYLH   
Prepro53 RKRTAEDHEVMKRLEAVMRDLDSLDHPEEAFERETRGFNQEEIANLFTKKEKR   
BioactiveMaximin H320YesILGPVLGLVGNALGGLIKKI 10.295.15