Maximin 4/H16

Entry Maximin 4/H16
Uniprot code B5L113
Fasta B5L113
Peptide names Maximin H16 Maximin 4/H16 Maximin 4
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial, antifungal, anticancer
Tissue Skin
Sequence MNFKYIVAVSFLIASAYARSVQNDEQSLSQRDVLEEESLREIRGIGGVLLSAGKAALKGL
AKVLAEKYANGKRTAEDHEVMKRLEAIMRDLDSLDHPEEASERETRGFNQDEIANLFTKK
EKRILGPVIGTIGNVLGGLIKKIG
Length 144
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro25 RSVQNDEQSLSQRDVLEEESLREIR   
BioactiveMaximin 427YesGIGGVLLSAGKAALKGLAKVLAEKYAN 1.031.03
Prepro53 GKRTAEDHEVMKRLEAIMRDLDSLDHPEEASERETRGFNQDEIANLFTKKEKR   
BioactiveMaximin H1620YesILGPVIGTIGNVLGGLIKKI