Maximin 11/H3

Entry Maximin 11/H3
Uniprot code B5L132
Fasta B5L132
Peptide names Maximin 11 Maximin 11/H3 Maximin H3
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial; Maximin H3: antibacterial, antifungal
Tissue Skin
Sequence MNFKYIVAVSILIASAYARSVQNDEQSLSQRDVLEEEESLREIRGIGGKILSGLKPALKG
AAKELAFTYLHRKRTAEDHEVMKRLEAVMRDLDSLDHPEEASERETRGFNQEEIANLFTK
KEKRILGPVLGLVGNALGGLIKKIG
Length 145
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSILIASAYA    
Prepro26 RSVQNDEQSLSQRDVLEEEESLREIR   
BioactiveMaximin 1127NoGIGGKILSGLKPALKGAAKELAFTYLH   
Prepro53 RKRTAEDHEVMKRLEAVMRDLDSLDHPEEASERETRGFNQEEIANLFTKKEKR   
BioactiveMaximin H320YesILGPVLGLVGNALGGLIKKI 10.295.15