Maximin 15/H3

Entry Maximin 15/H3
Uniprot code B5L138
Fasta B5L138
Peptide names Maximin 15 Maximin 15/H3 Maximin H3
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial; Maximin H3: antibacterial, antifungal
Tissue Skin, Brain
Sequence MNFKYIVAVSFLIASAYARSEENDEQSLSQRDVLEEESLREIRGIGTKILGGVKAALKGA
LKELASTYVNGKRTAEDHEVMKRLEAVMRDLDSLDYPEEAAERETRGFNQEEIANLFTKK
EKRILGPVLGLVGNALGGLIKKIG
Length 144
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Liu et al. / Journal of Proteome Research 10 (2011) 1806-1815. There are abundant antimicrobial peptides in brains of two kinds of Bombina toads; R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro25 RSEENDEQSLSQRDVLEEESLREIR   
BioactiveMaximin 1527YesGIGTKILGGVKAALKGALKELASTYVN10073.5
Prepro53 GKRTAEDHEVMKRLEAVMRDLDSLDYPEEAAERETRGFNQEEIANLFTKKEKR   
BioactiveMaximin H320YesILGPVLGLVGNALGGLIKKI 10.295.15