Entry | Maximin 25/H11 |
Uniprot code | B5L145 |
Fasta | B5L145 |
Peptide names | Maximin 25 Maximin H11 Maximin 25/H11 Maximin 3 |
Suborder | Archeobatrachia |
Family | Bombinatoridae |
Genus | Bombina |
Species | Bombina maxima |
Ecozone | Palearctic, Indomalaya |
Distribution | Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam |
Antimicrobial & other activities | antibacterial, antifungal, anticancer, anti-HIV-1, spermicidal |
Tissue | Skin, Brain |
Sequence | MNFKYIVAVSFLIASAYARGVQNDEQSLSQRDVLEEEESLREIRGIGGKILSGLKTALKG AAKELASTYLHRKRTAEEHEVMKRLEAVMRDLDSLDYPEEASERETRGFNQDEIANLFTK KEKRILGPVLGLVGSALGGLIKKIG |
Length | 145 |
Signal peptide class | Class-3 |
References: | |
1. for MIC/HC50 | R. Liu et al. / Journal of Proteome Research 10 (2011) 1806-1815. There are abundant antimicrobial peptides in brains of two kinds of Bombina toads |
2. for other activities | R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima |
Segment type | Name | Length | Amidated | Sequence | HC50 (μM) | MIC E. coli (μM) | MIC S. aureus (μM) |
Signal | 18 | MNFKYIVAVSFLIASAYA | |||||
Prepro | 26 | RGVQNDEQSLSQRDVLEEEESLREIR | |||||
Bioactive | Maximin 25 | 27 | Yes | GIGGKILSGLKTALKGAAKELASTYLH | 100 | 3.5 | 1.74 |
Prepro | 53 | RKRTAEEHEVMKRLEAVMRDLDSLDYPEEASERETRGFNQDEIANLFTKKEKR | |||||
Bioactive | Maximin H11 | 20 | No | ILGPVLGLVGSALGGLIKKI |