Gaegurin-6-RN

Entry Gaegurin-6-RN
Uniprot code C0ILJ2
Fasta C0ILJ2
Peptide names Gaegurin-6-RN Gaegurin-RN4 Gaegurin-GN4
Suborder Neobatrachia
Family Ranidae
Genus Hylarana
Species Hylarana nigrovittata
Ecozone Indomalaya
Distribution Nepal and West Bengal, Assam. and Meghalaya (India) as well as adjacent Bangladesh to Yunnan and Guangxi (China), Vietnam and south to Malaya
Antimicrobial & other activities antibacterial, antifungal, mast cell degranulation, histamine releasing
Tissue Skin
Sequence MFTMKKSLLLLFFLGTINLSLCEKERNAEEEKRDGDDETDVEVQKRFVGPVLKIAAGILP
TAICKIYKKC
Length 70
Signal peptide class Class-1
References:
1. for MIC/HC50 Y. Ma et al. / Genomics 95 (2010) 66-71. Peptidomics and genomics analysis of novel antimicrobial peptides from the frog, Rana nigrovittata


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTMKKSLLLLFFLGTINLSLC    
Prepro24 EKERNAEEEKRDGDDETDVEVQKR   
BioactiveGaegurin-6-RN24NoFVGPVLKIAAGILPTAICKIYKKC  0.46