Entry | Antimicrobial peptide |
Uniprot code | C3RSQ4 |
Fasta | C3RSQ4 |
Peptide names | Antimicrobial peptide Maximin 28 |
Suborder | Archeobatrachia |
Family | Bombinatoridae |
Genus | Bombina |
Species | Bombina maxima |
Ecozone | Palearctic, Indomalaya |
Distribution | Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam |
Antimicrobial & other activities | antibacterial, antifungal |
Tissue | Skin, Brain |
Sequence | MNFKYIVAVSFLIASAYARSEENDERSLSQRDVLEEESLREIRGIGTKFLGGVKTALKGA LKELASTYVNGKRTAEDHEVMKRLEAVMRDLDSLDYPEEAAERETRGFNEEEIANLFTKK EKRILGLVISTIGNVLGGLLKNLG |
Length | 144 |
Signal peptide class | Class-3 |
References: | |
1. for MIC/HC50 | R. Liu et al. / Journal of Proteome Research 10 (2011) 1806-1815. There are abundant antimicrobial peptides in brains of two kinds of Bombina toads |
Segment type | Name | Length | Amidated | Sequence | HC50 (μM) | MIC E. coli (μM) | MIC S. aureus (μM) |
Signal | 18 | MNFKYIVAVSFLIASAYA | |||||
Prepro | 25 | RSEENDERSLSQRDVLEEESLREIR | |||||
Bioactive | Maximin 28 | 27 | Yes | GIGTKFLGGVKTALKGALKELASTYVN | 100 | 3.43 | 1.72 |
Prepro | 53 | GKRTAEDHEVMKRLEAVMRDLDSLDYPEEAAERETRGFNEEEIANLFTKKEKR | |||||
Bioactive | Antimicrobial peptide | 20 | No | ILGLVISTIGNVLGGLLKNL |