Antimicrobial peptide

Entry Antimicrobial peptide
Uniprot code C3RSQ8
Fasta C3RSQ8
Peptide names Antimicrobial peptide Maximin H3
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial; Maximin H3: antibacterial, antifungal
Tissue Skin
Sequence MNFKYIVAVSFLIAFAYARSVQNDEQSLSQRDVLEEESLREIRGIGGKILGGFKTALKGA
AKELAATYLHRKRTAEEHEVMKRLEAVMRDLDSLDHPEEAFERETRGFNQDEIANFFTKK
EKRILGPVLGLVGNALGGLIKKIG
Length 144
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIAFAYA    
Prepro25 RSVQNDEQSLSQRDVLEEESLREIR   
BioactiveAntimicrobial peptide27NoGIGGKILGGFKTALKGAAKELAATYLH   
Prepro53 RKRTAEEHEVMKRLEAVMRDLDSLDHPEEAFERETRGFNQDEIANFFTKKEKR   
BioactiveMaximin H320YesILGPVLGLVGNALGGLIKKI 10.295.15