Antimicrobial peptide

Entry Antimicrobial peptide
Uniprot code C3RSS3
Fasta C3RSS3
Peptide names Antimicrobial peptide Maximin 4
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial, antifungal, anticancer
Tissue Skin
Sequence MNFKYIVAVSFLIASAYARSVQNDEQSLSQRDVLEEESLREIRGIGGVLLSAGKAALKGL
AKVLAEKYANGKRTAEDHEVMKRLEAVMRDLDSLDHPEEAFERETRGFNQDEIAKEKRIL
GPVLGLVGNTLGGLIKKIG
Length 139
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro25 RSVQNDEQSLSQRDVLEEESLREIR   
BioactiveMaximin 427YesGIGGVLLSAGKAALKGLAKVLAEKYAN 1.031.03
Prepro48 GKRTAEDHEVMKRLEAVMRDLDSLDHPEEAFERETRGFNQDEIAKEKR   
BioactiveAntimicrobial peptide20NoILGPVLGLVGNTLGGLIKKI