Antimicrobial peptide

Entry Antimicrobial peptide
Uniprot code C3RST8
Fasta C3RST8
Peptide names Antimicrobial peptide Maximin H3
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial; Maximin H3: antibacterial, antifungal
Tissue Skin
Sequence MNFKYIVAVSFLIASAYARSVQNDEQSLSQRDVLEEESLREIRGIGRKILGGLKTALKGA
AKELAATYLHRKRTAEEHEVMKRLEAVTRDLDSLDHPEEASERETRGFNQDEIANLFTKK
EKRILGPVLGLVGNALGGLIKKIG
Length 144
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro25 RSVQNDEQSLSQRDVLEEESLREIR   
BioactiveAntimicrobial peptide27NoGIGRKILGGLKTALKGAAKELAATYLH   
Prepro53 RKRTAEEHEVMKRLEAVTRDLDSLDHPEEASERETRGFNQDEIANLFTKKEKR   
BioactiveMaximin H320YesILGPVLGLVGNALGGLIKKI 10.295.15