Entry | Antimicrobial peptide |
Uniprot code | C3RSV1 |
Fasta | C3RSV1 |
Peptide names | Antimicrobial peptide Maximin 31 |
Suborder | Archeobatrachia |
Family | Bombinatoridae |
Genus | Bombina |
Species | Bombina maxima |
Ecozone | Palearctic, Indomalaya |
Distribution | Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam |
Antimicrobial & other activities | antibacterial |
Tissue | Skin, Brain |
Sequence | MNFKYIVAVSFLIASAYARSVEKDIQSLSQRDVLEEESLREIRGIGGALLSAGKSALKGL AKGLAEHFGKRTSEDHEVMKRLEAVMRDLDSLDHPEEASERETRGFNQEEIANRFTKKEK RILGPALGLVGNALGGLLKNLG |
Length | 142 |
Signal peptide class | Class-3 |
References: | |
1. for MIC/HC50 | R. Liu et al. / Journal of Proteome Research 10 (2011) 1806-1815. There are abundant antimicrobial peptides in brains of two kinds of Bombina toads |
Segment type | Name | Length | Amidated | Sequence | HC50 (μM) | MIC E. coli (μM) | MIC S. aureus (μM) |
Signal | 18 | MNFKYIVAVSFLIASAYA | |||||
Prepro | 25 | RSVEKDIQSLSQRDVLEEESLREIR | |||||
Bioactive | Maximin 31 | 25 | Yes | GIGGALLSAGKSALKGLAKGLAEHF | 100 | 31.7 | 15.8 |
Prepro | 53 | GKRTSEDHEVMKRLEAVMRDLDSLDHPEEASERETRGFNQEEIANRFTKKEKR | |||||
Bioactive | Antimicrobial peptide | 20 | No | ILGPALGLVGNALGGLLKNL |