Maximin 15/H23

Entry Maximin 15/H23
Uniprot code C3RSV5
Fasta C3RSV5
Peptide names Maximin 15 Maximin H23 Maximin 15/H23
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial
Tissue Skin, Brain
Sequence MNFKYIVAVSFLIASAYARSEENDEQSLSQRDILEEESLREIRGIGTKILGGVKAALKGA
LKELASTYVNGKRTAEDHEVMKRLEAVMRDLDSLDYPEEAAERETRGFNQEETANLFTKK
EKRILGPVISTIGNVLGGLLKNLG
Length 144
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Liu et al. / Journal of Proteome Research 10 (2011) 1806-1815. There are abundant antimicrobial peptides in brains of two kinds of Bombina toads


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro25 RSEENDEQSLSQRDILEEESLREIR   
BioactiveMaximin 1527YesGIGTKILGGVKAALKGALKELASTYVN10073.5
Prepro53 GKRTAEDHEVMKRLEAVMRDLDSLDYPEEAAERETRGFNQEETANLFTKKEKR   
BioactiveMaximin H2320YesILGPVISTIGNVLGGLLKNL