Antimicrobial peptide

Entry Antimicrobial peptide
Uniprot code C3RSW6
Fasta C3RSW6
Peptide names Antimicrobial peptide Maximin H5
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MNFKYIVAVSFLIASAYARSVQNDEQSLSQRDVLEEESLREIRGIGGKILSGLKTALKGA
AKELAATYLHRKRTAEEHEVMKRLEAVTRDLDSLDYPEEAFERETRGFNQDEIANLFTKK
EKRILGPVLGLVSDTLDDVLGILG
Length 144
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Lai et al. / BBRC 295 (2002) 796-799. An anionic antimicrobial peptide from toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro25 RSVQNDEQSLSQRDVLEEESLREIR   
BioactiveAntimicrobial peptide27NoGIGGKILSGLKTALKGAAKELAATYLH   
Prepro53 RKRTAEEHEVMKRLEAVTRDLDSLDYPEEAFERETRGFNQDEIANLFTKKEKR   
BioactiveMaximin H520YesILGPVLGLVSDTLDDVLGIL >100.0080