Entry | Antimicrobial peptide |
Uniprot code | C3RSX7 |
Fasta | C3RSX7 |
Peptide names | Antimicrobial peptide Maximin 42 |
Suborder | Archeobatrachia |
Family | Bombinatoridae |
Genus | Bombina |
Species | Bombina maxima |
Ecozone | Palearctic, Indomalaya |
Distribution | Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam |
Antimicrobial & other activities | antibacterial |
Tissue | Skin, Brain |
Sequence | MNFKYIVAVSFLIASVYARSVKNDEQSLSQRDVLEEESLREIRSIGAKILGGVKTFFKGA LKELAFTYLQRKRTAEEQHEVMKRLEAVMRDLDSLDHPEEAFERETRGFNQEEIANLFTK KEKRVLGPVLGLVSNALGGLLG |
Length | 142 |
Signal peptide class | Class-3 |
References: | |
1. for MIC/HC50 | R. Liu et al. / Journal of Proteome Research 10 (2011) 1806-1815. There are abundant antimicrobial peptides in brains of two kinds of Bombina toads |
Segment type | Name | Length | Amidated | Sequence | HC50 (μM) | MIC E. coli (μM) | MIC S. aureus (μM) |
Signal | 18 | MNFKYIVAVSFLIASVYA | |||||
Prepro | 25 | RSVKNDEQSLSQRDVLEEESLREIR | |||||
Bioactive | Maximin 42 | 27 | Yes | SIGAKILGGVKTFFKGALKELAFTYLQ | 12.92 | ||
Prepro | 54 | RKRTAEEQHEVMKRLEAVMRDLDSLDHPEEAFERETRGFNQEEIANLFTKKEKR | |||||
Bioactive | Antimicrobial peptide | 17 | No | VLGPVLGLVSNALGGLL |