Antimicrobial peptide

Entry Antimicrobial peptide
Uniprot code C3RSX7
Fasta C3RSX7
Peptide names Antimicrobial peptide Maximin 42
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial
Tissue Skin, Brain
Sequence MNFKYIVAVSFLIASVYARSVKNDEQSLSQRDVLEEESLREIRSIGAKILGGVKTFFKGA
LKELAFTYLQRKRTAEEQHEVMKRLEAVMRDLDSLDHPEEAFERETRGFNQEEIANLFTK
KEKRVLGPVLGLVSNALGGLLG
Length 142
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Liu et al. / Journal of Proteome Research 10 (2011) 1806-1815. There are abundant antimicrobial peptides in brains of two kinds of Bombina toads


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASVYA    
Prepro25 RSVKNDEQSLSQRDVLEEESLREIR   
BioactiveMaximin 4227YesSIGAKILGGVKTFFKGALKELAFTYLQ  12.92
Prepro54 RKRTAEEQHEVMKRLEAVMRDLDSLDHPEEAFERETRGFNQEEIANLFTKKEKR   
BioactiveAntimicrobial peptide17NoVLGPVLGLVSNALGGLL