Entry | Maximin 42/H4 |
Uniprot code | C3RSX8 |
Fasta | C3RSX8 |
Peptide names | Maximin 42/H4 Maximin 42 Maximin H4 |
Suborder | Archeobatrachia |
Family | Bombinatoridae |
Genus | Bombina |
Species | Bombina maxima |
Ecozone | Palearctic, Indomalaya |
Distribution | Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam |
Antimicrobial & other activities | antibacterial; Maximin H4: antibacterial, antifungal |
Tissue | Skin, Brain |
Sequence | MNFKYIVAVSFLIASAYARSEENDEQSLSQRDVLEEESLREIRSIGAKILGGVKTFFKGA LKELAFTYLQRKRTAEEQHEVMKRLEAVMRDLDSLDHPEEAFERETRGFNQEEIANHFTK KEKRILGPVISKIGGVLGGLLKNLG |
Length | 145 |
Signal peptide class | Class-3 |
References: | |
1. for MIC/HC50 | R. Liu et al. / Journal of Proteome Research 10 (2011) 1806-1815. There are abundant antimicrobial peptides in brains of two kinds of Bombina toads; R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima |
Segment type | Name | Length | Amidated | Sequence | HC50 (μM) | MIC E. coli (μM) | MIC S. aureus (μM) |
Signal | 18 | MNFKYIVAVSFLIASAYA | |||||
Prepro | 25 | RSEENDEQSLSQRDVLEEESLREIR | |||||
Bioactive | Maximin 42 | 27 | Yes | SIGAKILGGVKTFFKGALKELAFTYLQ | 12.92 | ||
Prepro | 54 | RKRTAEEQHEVMKRLEAVMRDLDSLDHPEEAFERETRGFNQEEIANHFTKKEKR | |||||
Bioactive | Maximin H4 | 20 | Yes | ILGPVISKIGGVLGGLLKNL | 6.12 | 3.06 |