Maximin 2/H5

Entry Maximin 2/H5
Uniprot code C3RSY2
Fasta C3RSY2
Peptide names Maximin 2/H5 Maximin 2 Maximin H5
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin
Sequence MNFKYIVAVSFLIASAYARSEENDEQSLSQRDILEEESLREIRGIGTKILGGVKTALKGA
LKELASTYVNGKRTAEEHEVMKRLEAVMRDLDSLDYPEEASERETRGFNQDEIANLFTKK
EKRILGPVLGLVSDTLDDVLGILG
Length 144
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima; R. Lai et al. / BBRC 295 (2002) 796-799. An anionic antimicrobial peptide from toad Bombina maxima


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro25 RSEENDEQSLSQRDILEEESLREIR   
BioactiveMaximin 227YesGIGTKILGGVKTALKGALKELASTYVN 7.227.22
Prepro53 GKRTAEEHEVMKRLEAVMRDLDSLDYPEEASERETRGFNQDEIANLFTKKEKR   
BioactiveMaximin H520YesILGPVLGLVSDTLDDVLGIL >100.0080