Entry | Antimicrobial peptide |
Uniprot code | C3RSY6 |
Fasta | C3RSY6 |
Peptide names | Antimicrobial peptide Maximin 4 |
Suborder | Archeobatrachia |
Family | Bombinatoridae |
Genus | Bombina |
Species | Bombina maxima |
Ecozone | Palearctic, Indomalaya |
Distribution | Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam |
Antimicrobial & other activities | antibacterial, antifungal, anticancer |
Tissue | Skin |
Sequence | MNFKYIVAVSFLIASVYARSVQNDEQSLSQRDVLEEESLREIRGIGGVLLSAGKAALKGL AKVLAEKYANGKRTAEDHEVMKRLEAVMRDLDSLDHPEEAFERETRGFNQDEIAKEKRIL GPVLGLVDNALGGLIKKIG |
Length | 139 |
Signal peptide class | Class-3 |
References: | |
1. for MIC/HC50 | R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima |
Segment type | Name | Length | Amidated | Sequence | HC50 (μM) | MIC E. coli (μM) | MIC S. aureus (μM) |
Signal | 18 | MNFKYIVAVSFLIASVYA | |||||
Prepro | 25 | RSVQNDEQSLSQRDVLEEESLREIR | |||||
Bioactive | Maximin 4 | 27 | Yes | GIGGVLLSAGKAALKGLAKVLAEKYAN | 1.03 | 1.03 | |
Prepro | 48 | GKRTAEDHEVMKRLEAVMRDLDSLDHPEEAFERETRGFNQDEIAKEKR | |||||
Bioactive | Antimicrobial peptide | 20 | No | ILGPVLGLVDNALGGLIKKI |