Maximin 8/H7

Entry Maximin 8/H7
Uniprot code C3RSZ2
Fasta C3RSZ2
Peptide names Maximin 8 Maximin 8/H7 Maximin H7
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial; Maximin H7: antibacterial, antifungal
Tissue Skin
Sequence MKFKYIVAVSFLIASAYARSEENDEQSLSQRDVLEEESLREIRGIGTKILGGLKTAVKGA
LKELASTYVNGKRTAEDHEVMKRLEAVMRDLDSLDYPEEASERETRGFNQEEIANLFTKK
EKRILGPVIKTIGGVIGGLLKNLG
Length 144
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Liu et al. / Journal of Proteome Research 10 (2011) 1806-1815. There are abundant antimicrobial peptides in brains of two kinds of Bombina toads


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MKFKYIVAVSFLIASAYA    
Prepro25 RSEENDEQSLSQRDVLEEESLREIR   
BioactiveMaximin 827NoGIGTKILGGLKTAVKGALKELASTYVN   
Prepro53 GKRTAEDHEVMKRLEAVMRDLDSLDYPEEASERETRGFNQEEIANLFTKKEKR   
BioactiveMaximin H720YesILGPVIKTIGGVIGGLLKNL90 4.76