Maximin 78

Entry Maximin 78
Uniprot code C3RTK3
Fasta C3RTK3
Peptide names Maximin 78 Antimicrobial peptide
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial, antifungal
Tissue Brain
Sequence MNFKYIVAVSFFIASAYARSEENEIQSLSQRDVLEEESLREIRGIGGALLSVGKLALKGL
ANVLADKFANGKRTAEDHEVMKRLEAVMRDLDSLYYPEEASERETRGFNQEEIANLFTKK
RETHFGANTRFGW
Length 133
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Liu et al. / Journal of Proteome Research 10 (2011) 1806-1815. There are abundant antimicrobial peptides in brains of two kinds of Bombina toads


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFFIASAYA    
Prepro25 RSEENEIQSLSQRDVLEEESLREIR   
BioactiveMaximin 7827YesGIGGALLSVGKLALKGLANVLADKFAN50 1.8
Prepro51 GKRTAEDHEVMKRLEAVMRDLDSLYYPEEASERETRGFNQEEIANLFTKKR   
BioactiveAntimicrobial peptide12NoETHFGANTRFGW