Maximin 5/H55

Entry Maximin 5/H55
Uniprot code C3RTL1
Fasta C3RTL1
Peptide names Maximin 5/H55 Maximin 5 Maximin H55
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina maxima
Ecozone Palearctic, Indomalaya
Distribution Yunnan, southwestern Sichuan, Hubei, Guizhou, and northern Guangxi, China; adjacent northern Vietnam
Antimicrobial & other activities antibacterial, antifungal
Tissue Brain
Sequence MNFKYIVAVSFLIASAYARSVKNDEQSLSQRDVLEEESLREIRSIGAKILGGVKTFFKGA
LKELASTYLQRKRTAEEQHEVMKRLEAVMRDLDSSDHPEEASERETRGFNQEEIANLFTK
KEKRILGPVISTIGNALGGLLKNLG
Length 145
Signal peptide class Class-3
References:
1. for MIC/HC50 R. Lai et al. / Peptides 23 (2002) 427-435. Antimicrobial peptides from skin secretions of Chinese red belly toad Bombina maxima; R. Liu et al. / Journal of Proteome Research 10 (2011) 1806-1815. There are abundant antimicrobial peptides in brains of two kinds of Bombina toads


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSFLIASAYA    
Prepro25 RSVKNDEQSLSQRDVLEEESLREIR   
BioactiveMaximin 527NoSIGAKILGGVKTFFKGALKELASTYLQ  1.27
Prepro54 RKRTAEEQHEVMKRLEAVMRDLDSSDHPEEASERETRGFNQEEIANLFTKKEKR   
BioactiveMaximin H5520YesILGPVISTIGNALGGLLKNL32>50.00>50.00