Amolopin-2e

Entry Amolopin-2e
Uniprot code C5H0D6
Fasta C5H0D6
Peptide names Amolopin-2e Temporin-ALd
Suborder Neobatrachia
Family Ranidae
Genus Amolops
Species Amolops loloensis
Ecozone Palearctic
Distribution High-gradients streams in Zhaojue, Mianning, Hongya, Luding, and Baoxing in southern Sichuan, China, 1840-3700 m elevation
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin
Sequence MFTMKKSLLLLFFLGTIHLSLCEQERNAEEERRDDLGERQAEVEKRFLPIAGKLLSGLSG
LLGK
Length 64
Signal peptide class Class-1
References:
1. for MIC/HC50 M. Wang et al. / Comparative Biochemistry and Physiology, Part B 155 (2010) 72-76. Five novel antimicrobial peptides from skin secretions of the frog, Amolops loloensis


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTMKKSLLLLFFLGTIHLSLC    
Prepro24 EQERNAEEERRDDLGERQAEVEKR   
BioactiveAmolopin-2e16YesFLPIAGKLLSGLSGLL 0.780.78