Ranatuerin-1

Entry Ranatuerin-1
Uniprot code C5IBR9
Fasta C5IBR9
Peptide names Ranatuerin-1
Suborder Neobatrachia
Family Ranidae
Genus Lithobates
Species Lithobates catesbeianus
Ecozone Nearctic, Neotropic
Distribution Eastern North America, except southern Florida, north to Nova Scotia, New Brunswick, southern Quebec, and southern Ontario (Canada), west to the central plains and south to Hidalgo, Puebla, and adjacent Veracruz (Mexico); introduced on Cuba, Isla de Juventud (= Isla de Pinos), Puerto Rico, Hispaniola, and Jamaica in the Antilles; introduced widely in the rest of the world including the Netherlands, Bordeaux region of France, Belgium, northern Italy, western Spain, Crete, Malaya (Malaysia), Java, Bali, Japan, southern and western Mexico, northern Thailand, Korea, and Taiwan (China)
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin
Sequence MFTLKKSLLLLFFLGTITLSLCEQERGADEEEGNGEKEIKRSMLSVLKNLGKVGLGFVAC
KINKQC
Length 66
Signal peptide class Class-1
References:
1. for MIC/HC50 J.M. Conlon et al. / Biochimica et Biophysica Acta 1696 (2004) 1-14. Antimicrobial peptides from ranid frogs: taxonomic and phylogenetic markers and a potential source of new therapeutic agents


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSLLLLFFLGTITLSLC    
Prepro19 EQERGADEEEGNGEKEIKR   
BioactiveRanatuerin-125NoSMLSVLKNLGKVGLGFVACKINKQC1501325