Entry
Japonicin-1NPa
Uniprot code
D0ES73
Fasta
D0ES73
Peptide names
Japonicin-1NPa
Suborder
Neobatrachia
Family
Ranidae
Genus
Nanorana
Species
Nanorana parkeri
Ecozone
Palearctic, Indomalaya
Distribution
Southern third of Xizang (China) and high elevations of north-central Nepal; expected in Himalayan Bhutan, northeastern Kashmir, and India (Sikkim)
Antimicrobial & other activities
antibacterial, antioxidant, mast cell degranulation
Tissue
Skin
Sequence
MFTLKKTLFLVFFLGMVSLSLCEQERHAHEETSNDPTEEENAAGNEESGEEGDMEKRFLL
Length
71
Signal peptide class
Class-1
References:
1. for MIC/HC50
Z. Lu et al. / Biochimie 92 (2010) 475-481. Novel families of antimicrobial peptides with multiple functions from skin of Xizang plateau frog, Nanorana parkeri
Segment type
Name
Length
Amidated
Sequence
HC50 (μM)
MIC E. coli (μM)
MIC S. aureus (μM)
Signal
22
MFTLKKTLFLVFFLGMVSLSLC
Prepro 35 EQERHAHEETSNDPTEEENAAGNEESGEEGDMEKR Bioactive Japonicin-1NPa 14 No FLLFPLMCKIQGKC >61.00 22.85