Ranatuerin-2SHb

Entry Ranatuerin-2SHb
Uniprot code D5LXG2
Fasta D5LXG2
Peptide names OGTI Ranatuerin-2SHb Ranatuerin-2R-RA2 Ranatuerin-2-MG1 Andersonin-W2
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana schmackeri
Ecozone Palearctic, Indomalaya
Distribution Southern and south-central China in Henan, Shaanxi, Gansu, Sichuan, Guizhou, Hubei, Anhui, Jiangsu, Zhejiang, Hunan, Guangdong and Guangxi Provinces, at 200-1400 m elevation; reports from Vietnam and Thailand require confirmation
Antimicrobial & other activities antibacterial, serine protease inhibitor
Tissue Skin
Sequence MFTMKKSLLLLFFLGFISLSLCEEERDANEERRDDPDESEANEGEAKVEEIKRAVNIPFK
VHFRCKAAFC
Length 70
Signal peptide class Class-1
References:
1. for MIC/HC50 X. Yang et al. / Journal of Proteome Research 11 (2012) 306-319. Extremely Abundant Antimicrobial Peptides Existed in the Skins of Nine Kinds of Chinese Odorous Frogs
2. for other activities J. Li et al. / Biochimie 90 (2008) 1356-1361. A small trypsin inhibitor from the frog of Odorrana grahami


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTMKKSLLLLFFLGFISLSLC    
Prepro31 EEERDANEERRDDPDESEANEGEAKVEEIKR   
BioactiveRanatuerin-2SHb17NoAVNIPFKVHFRCKAAFC 10.355.18