Temporin-TOa

Entry Temporin-TOa
Uniprot code D5MTH4
Fasta D5MTH4
Peptide names Temporin-TOa
Suborder Neobatrachia
Family Ranidae
Genus Rana
Species Rana tagoi okiensis
Ecozone Palearctic
Distribution Mountain regions of Honshu, Shikoku, and Kyushu Islands as well as Togoshima in the Oki Archipelago and Yakushima in the Tanegashima Group, Japan
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin, Brain
Sequence MFTLKKSLLLLFFLGTINLSLCEEERNAEEERRDDPEETNVEVEKRFLPILGKLLSGFLG
K
Length 61
Signal peptide class Class-1
References:
1. for MIC/HC50 J.M. Conlon et al. / Toxicon 55 (2010) 430-435. Evidence from the primary structures of dermal antimicrobial peptides that Rana tagoi okiensis and Rana tagoi tagoi (Ranidae) are not conspecific subspecies


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSLLLLFFLGTINLSLC    
Prepro24 EEERNAEEERRDDPEETNVEVEKR   
BioactiveTemporin-TOa13YesFLPILGKLLSGFL >160.0010