Entry
Nigrosin-MG2
Uniprot code
E1AWC3
Fasta
E1AWC3
Peptide names
Grahamin-1 Nigrosin-MG2 Nigrosin-OG17 Nigrosin-OG20
Suborder
Neobatrachia
Family
Ranidae
Genus
Odorrana
Species
Odorrana margaretae
Ecozone
Palearctic, Indomalaya
Distribution
Gansu, Guangxi, eastern Xizang, Sichuan, Hubei, Hunan, Guizhou, and southern Shaanxi, China, 390-1500 m elevation; mountains of northern Vientam (Lao Cai and Lai Chau provinces), 1900-2500 m
Antimicrobial & other activities
antibacterial, antifungal
Tissue
Skin
Sequence
MFTSKKPLLLLFFLGTINLSLCQDETNAEEERRDEEVAKMEEIKRGLLSGILGAGKNIVC GLSGLC
Length
66
Signal peptide class
Class-1
References:
1. for MIC/HC50
X. Xu et al. / Toxicon 47 (2006) 459-464. Two antimicrobial peptides from skin secretions of Rana grahami
Segment type
Name
Length
Amidated
Sequence
HC50 (μM)
MIC E. coli (μM)
MIC S. aureus (μM)
Signal
22
MFTSKKPLLLLFFLGTINLSLC
Prepro 23 QDETNAEEERRDEEVAKMEEIKR Bioactive Nigrosin-MG2 21 No GLLSGILGAGKNIVCGLSGLC 3.86 1.29