Phylloseptin-1

Entry Phylloseptin-1
Uniprot code E3PQH3
Fasta E3PQH3
Peptide names Phylloseptin-1 PSN-1
Suborder Neobatrachia
Family Hylidae
Genus Phyllomedusa
Species Phyllomedusa sauvagii
Ecozone Neotropic
Distribution The Chacoan region of eastern Bolivia, northern Paraguay, Mato Grosso do Sul (Brazil), and northern Argentina
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin
Sequence MDILKKSLFLVLFLGLVSLSICEEEKRETEEEEHDQEEDDKSEEKRFLSLIPHIVSGVAS
IAKHFG
Length 66
Signal peptide class Class-1
References:
1. for MIC/HC50 R. Zhang et al. / Molecular Immunology 47 (2010) 2030-2037. Phylloseptin-1 (PSN-1) from Phyllomedusa sauvagei skin secretion: A novel broad-spectrum antimicrobial peptide with antibiofilm activity


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MDILKKSLFLVLFLGLVSLSIC    
Prepro24 EEEKRETEEEEHDQEEDDKSEEKR   
BioactivePhylloseptin-119YesFLSLIPHIVSGVASIAKHF30805