Odorranain-B-RA1

Entry Odorranain-B-RA1
Uniprot code E3SZA7
Fasta E3SZA7
Peptide names Odorranain-B-RA1 Ranacyclin B5
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana andersonii
Ecozone Indomalaya
Distribution Northeastern India, Upper Myanmar, and northern Thailand to western Yunnan, China; south into Vietnam and Laos
Antimicrobial & other activities antibacterial, antifungal, trypsin inhibitor
Tissue Skin
Sequence MFTLKKSLLLLFFLGIVSLSSCEQERDADEEDGGEVTGEEVKRAALRGCWTKSIPPKPCS
GKR
Length 63
Signal peptide class Class-1
References:
1. for MIC/HC50 X. Yan et al. / Amino Acids (2011) DOI 10.1007/s00726-011-1079-8. Bi-functional peptides with both trypsin-inhibitory and antimicrobial activities are frequent defensivemolecules in Ranidae amphibian skins


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTLKKSLLLLFFLGIVSLSSC    
Prepro21 EQERDADEEDGGEVTGEEVKR   
BioactiveOdorranain-B-RA120NoAALRGCWTKSIPPKPCSGKR  5.8