Esculentin-2V-HN1

Entry Esculentin-2V-HN1
Uniprot code E7EKC7
Fasta E7EKC7
Peptide names Esculentin-2V-HN1 Esculentin-2V
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana hainanensis
Ecozone Indomalaya
Distribution Southern and southwestern Hainan Island, China, 200-900 m elevation
Antimicrobial & other activities antibacterial
Tissue Skin
Sequence MFTMKKPLLVLFFLGTISLSLCQEERAADEEDNGEVEEVKRGIFTLFKGAAKLLGKTLAK
EAGKTGLELMACKVTNQC
Length 78
Signal peptide class Class-1
References:
1. for MIC/HC50 T. Chen et al. / Genomics 87 (2006) 638-644. Cloning from tissue surrogates: Antimicrobial peptide (esculentin) cDNAs from the defensive skin secretions of Chinese ranid frogs


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTMKKPLLVLFFLGTISLSLC    
Prepro19 QEERAADEEDNGEVEEVKR   
BioactiveEsculentin-2V-HN137NoGIFTLFKGAAKLLGKTLAKEAGKTGLELMACKVTNQC 2.84.4