| Entry | Dermorphin |
| Uniprot code | O93456 |
| Fasta | O93456 |
| Peptide names | Dermorphin [Ile2]-deltorphin |
| Suborder | Neobatrachia |
| Family | Hylidae |
| Genus | Pachymedusa |
| Species | Pachymedusa dacnicolor |
| Ecozone | Neotropic |
| Distribution | Pacific lowlands of Mexico from southern Sonora south (including the Balsas Depression to the state of Mexico) to the Isthmus of Tehuantepec |
| Antimicrobial & other activities | inhibition of ileum cells contraction, inhibition of vas deferens cells contraction, mu-receptor affinity, delta-receptor affinity, antinociceptive |
| Tissue | Skin |
| Sequence | MSFLKKSLLLILFLGLVSLSICEEQKREIEEDENENEEERNEASEMKRYAFGYPSGEEKK IKRETEEDENENEEERNEASEMKRYAFGYPSGEEKKIKRETEEDENENEEERNEASEMKR YAFGYPSGEEKKIKRETEEDENENEEERNEGSEMKRYAFGYPSGGAKRMKRKPVEEEENH VAGSKMKRYIFHLMDGEVKKI |
| Length | 201 |
| Signal peptide class | Class-1 |
| References: | |
| 2. for other activities | K. Richter et al. / PNAS 87 (1990) 4836-4839. cDNAs encoding [D-Ala2]deltorphin precursors from skin of Phyllomedusa bicolor also contain genetic information for three dermorphin-related opioid peptides |
| Segment type | Name | Length | Amidated | Sequence | HC50 (μM) | MIC E. coli (μM) | MIC S. aureus (μM) |
| Signal | 22 | MSFLKKSLLLILFLGLVSLSIC | |||||
| Prepro | 26 | EEQKREIEEDENENEEERNEASEMKR | |||||
| Bioactive | Dermorphin | 7 | No | YAFGYPS | |||
| Prepro | 29 | GEEKKIKRETEEDENENEEERNEASEMKR | |||||
| Bioactive | Dermorphin | 7 | No | YAFGYPS | |||
| Prepro | 29 | GEEKKIKRETEEDENENEEERNEASEMKR | |||||
| Bioactive | Dermorphin | 7 | No | YAFGYPS | |||
| Prepro | 29 | GEEKKIKRETEEDENENEEERNEGSEMKR | |||||
| Bioactive | Dermorphin | 7 | No | YAFGYPS | |||
| Prepro | 25 | GGAKRMKRKPVEEEENHVAGSKMKR | |||||
| Bioactive | [Ile2]-deltorphin | 7 | No | YIFHLMD |