| Entry | Dermorphin-1 |
| Uniprot code | P05422 |
| Fasta | P05422 |
| Peptide names | Deltorphin Dermorphin-1 Dermorphin |
| Suborder | Neobatrachia |
| Family | Hylidae |
| Genus | Phyllomedusa |
| Species | Phyllomedusa sauvagii |
| Ecozone | Neotropic |
| Distribution | The Chacoan region of eastern Bolivia, northern Paraguay, Mato Grosso do Sul (Brazil), and northern Argentina |
| Antimicrobial & other activities | inhibition of ileum cells contraction, inhibition of vas deferens cells contraction, mu-receptor affinity, delta-receptor affinity, antinociceptive |
| Tissue | Skin |
| Sequence | MSFLKKSLLLILFLGLVSLSVCKEEKRETEEENENEENHEEGSEMKRYMFHLMDGEAKKR DSEENEIEENHEEGSEMKRYAFGYPSGEAKKIKRVSEEENENEENHEEGSEMKRYAFGYP SGEAKKIKRESEEEKEIEENHEEGSEMKRYAFGYPSGEAKKIKRESEEENENEENHEEGS EMKRYAFGYPSGEAKKM |
| Length | 197 |
| Signal peptide class | Class-1 |
| References: | |
| 2. for other activities | K. Richter et al. / PNAS 87 (1990) 4836-4839. cDNAs encoding [D-Ala2]deltorphin precursors from skin of Phyllomedusa bicolor also contain genetic information for three dermorphin-related opioid peptides |
| Segment type | Name | Length | Amidated | Sequence | HC50 (μM) | MIC E. coli (μM) | MIC S. aureus (μM) |
| Signal | 22 | MSFLKKSLLLILFLGLVSLSVC | |||||
| Prepro | 25 | KEEKRETEEENENEENHEEGSEMKR | |||||
| Bioactive | Deltorphin | 7 | No | YMFHLMD | |||
| Prepro | 25 | GEAKKRDSEENEIEENHEEGSEMKR | |||||
| Bioactive | Dermorphin | 7 | No | YAFGYPS | |||
| Prepro | 28 | GEAKKIKRVSEEENENEENHEEGSEMKR | |||||
| Bioactive | Dermorphin | 7 | No | YAFGYPS | |||
| Prepro | 28 | GEAKKIKRESEEEKEIEENHEEGSEMKR | |||||
| Bioactive | Dermorphin | 7 | No | YAFGYPS | |||
| Prepro | 28 | GEAKKIKRESEEENENEENHEEGSEMKR | |||||
| Bioactive | Dermorphin | 7 | No | YAFGYPS |