Grahamin-1

Entry Grahamin-1
Uniprot code P0C2A4
Fasta P0C2A4
Peptide names Grahamin-1 Nigrosin-MG2 Nigrosin-OG17 Nigrosin-OG20
Suborder Neobatrachia
Family Ranidae
Genus Odorrana
Species Odorrana grahami
Ecozone Palearctic, Indomalaya
Distribution Sichuan, Guizhou, and central and western Yunnan, China; a distantly alloparic population present in southern Shanxi, China: presumably to be found in eastern Myanmar along the Yunna, China, border; reported in Lao Cai and Lai Chau provinces, Vietnam, 1150-3200 m elevation
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin
Sequence MFTMKKSMLLLFFLGTISLSLCEQERNADEEERRDEEVAKMEEIKRGLLSGILGAGKNIV
CGLSGLC
Length 67
Signal peptide class Class-1
References:
1. for MIC/HC50 X. Xu et al. / Toxicon 47 (2006) 459-464. Two antimicrobial peptides from skin secretions of Rana grahami


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   22   MFTMKKSMLLLFFLGTISLSLC    
Prepro24 EQERNADEEERRDEEVAKMEEIKR   
BioactiveGrahamin-121NoGLLSGILGAGKNIVCGLSGLC 3.861.29