Bombinin-like peptides 1

Entry Bombinin-like peptides 1
Uniprot code P29002
Fasta P29002
Peptide names Bombinin-like peptide 1 Bombinin-like peptides 1 BLP-1 GH-1 peptide
Suborder Archeobatrachia
Family Bombinatoridae
Genus Bombina
Species Bombina orientalis
Ecozone Palearctic
Distribution Southern part of Russian Far East (Primorye Region and a few localities in the Khabarovskii Region); northeastern China (from northeastern Inner Mongolia and Heilongjiang south to southern Liaoning, with one locality in the Beijing area and other records in eastern Shandong and eastern Jiangsu) and Korea; Tsushima and Kyushu Islands, Japan
Antimicrobial & other activities antibacterial, antifungal
Tissue Skin
Sequence MNFKYIVAVSILIASAYARSEENDIQSLSQRDVLEEESLREIRGIGASILSAGKSALKGL
AKGLAEHFANGKRTAEDHEVMKRLEAAIQSLSQRDVLEEESLREIRGIGASILSAGKSAL
KGLAKGLAEHFANGKRTAEEHEVMKRLEAVMRDLDSLDYPEEASEMETRSFNQEEIANLY
TKKEKRILGPILGLVSNALGGLLG
Length 204
Signal peptide class Class-3
References:
1. for MIC/HC50 M. Simmaco et al. / Biochimica et Biophysica Acta 1788 (2009) 1551-1555. Bombinins, antimicrobial peptides from Bombina species


Segment type Name Length Amidated Sequence HC50 (μM) MIC E. coli (μM) MIC S. aureus (μM)
Signal   18   MNFKYIVAVSILIASAYA    
Prepro25 RSEENDIQSLSQRDVLEEESLREIR   
BioactiveBombinin-like peptide 127YesGIGASILSAGKSALKGLAKGLAEHFAN 1.53.4
Prepro36 GKRTAEDHEVMKRLEAAIQSLSQRDVLEEESLREIR   
BioactiveBombinin-like peptide 127YesGIGASILSAGKSALKGLAKGLAEHFAN 1.53.4
Prepro53 GKRTAEEHEVMKRLEAVMRDLDSLDYPEEASEMETRSFNQEEIANLYTKKEKR   
BioactiveGH-1 peptide18NoILGPILGLVSNALGGLLG